The NETWISE research team is a multi-institutional research group that conducts research on questions related to how social and professional networks matter in the careers of academic scientists, with special attention to women and underrepresented minorities. Two large NSF awards provided the foundation for the team and its on-going research. The sequential grants enabled the development of robust primary data sets on the professional networks, and career and collaborative experiences of academic scientists and engineers in the United States. NETWISE I focused on the professional networks of scientists in Carnegie Research I institutions. NETWISE II expanded the focus to include a broader range of postsecondary institutions (Research II, liberal arts, and master’s comprehensive institutions), enabling examination of academic science and engineering careers in diverse institutional settings. The research design blended primary survey data with life-time bibliometric data, and institutional data.